MediWeek

Sleep duration is increasingly recognized as a key determinant of systemic health and ageing. Sleep plays a fundamental role in maintaining metabolic, cardiovascular, immune, and neurological health. While both short and long sleep have been linked to adverse clinical outcomes, their effects on biological ageing across multiple organ systems remain incompletely understood. Emerging evidence suggests […]

Poor balance can make simple tasks difficult and increase the risk of falls, joint disorders, and reduced stability. Maintaining balance requires coordination between the trunk and lower limbs, along with proper alignment of the body’s center of gravity. Disruption of this coordination may contribute to inefficient movement and low back pain. Low-intensity exercises performed in

Heart failure with preserved ejection fraction (HFpEF) is a growing global health burden, accounting for more than half of all heart failure cases. Obesity has emerged as a major independent risk factor for HFpEF, contributing to systemic inflammation, neurohormonal activation, myocardial fibrosis (stiffening of the heart muscle, thus limiting its ability to pump blood) and

Mental health disorders, such as anxiety and depression, are becoming increasingly common worldwide. Lifestyle and dietary factors, including coffee consumption, are being explored for their role in mental health, though evidence has been inconsistent. Emerging evidence suggests a J-shaped relationship, in which moderate intake may be beneficial, whereas higher intake may be harmful. Coffee contains bioactive

Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, driven by major events such as myocardial infarction, heart failure, and stroke. Lifestyle behaviors such as sleep, physical activity, and diet are the key determinants of cardiovascular health. However, they have always been studied in isolation. Emerging evidence suggests that these behaviors interact synergistically, influencing

Lifestyle factors are increasingly recognized as important determinants of cognitive health. Previous research has shown that home cooking is associated with a lower risk of conditions such as type 2 diabetes, obesity, and cardiovascular disease, along with potential mental health benefits.1 Cooking at home promotes healthier eating habits, including increased intake of fruits and vegetables

Sleep patterns are increasingly recognized as important determinants of cardiometabolic health. While sleep duration has been widely studied, the impact of sleep regularity and variability on long-term cardiovascular outcomes remains less clearly understood. Emerging evidence suggests that inconsistent sleep schedules may disrupt circadian rhythms, contributing to adverse metabolic and cardiovascular effects. However, large-scale prospective data

Physical exercise is widely known to improve cognitive function and memory, but the underlying neural mechanisms remain incompletely understood. In particular, hippocampal sharp-wave ripples—the key neurophysiological markers of memory processing—are thought to play a central role in learning and memory consolidation. Recent evidence suggests that interactions between the hippocampus and cortical networks, especially the default

Dementia significantly affects the quality of life in older adults, with global cases projected to reach nearly 150 million by 2050. Early prevention through modifiable lifestyle factors, particularly diet, has gained increasing attention. While unhealthy dietary habits such as high intake of red and processed meat have been linked to poorer cognitive outcomes, healthier diets

Sleep duration plays a critical role in metabolic health, particularly in regulating insulin sensitivity and cardiometabolic risk. Both insufficient and excessive sleep have been linked to insulin resistance and metabolic disorders. However, association between weekday sleep duration and insulin sensitivity remains unclear. Understanding how sleep patterns influence metabolic markers such as estimated glucose disposal rate